Fc VARIANTS WITH ALTERED BINDING TO FcRn
The present application relates to a variant Fc region comprising at least one modification relative to a wild-type human Fc region, where the modification selected from the group consisting of 434S, 252Y/428L, 252Y/434S, and 428L/434S, and the numbering is according to the EU index.
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Main Authors | , , , , |
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Format | Patent |
Language | English |
Published |
25.06.2009
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Subjects | |
Online Access | Get full text |
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Summary: | The present application relates to a variant Fc region comprising at least one modification relative to a wild-type human Fc region, where the modification selected from the group consisting of 434S, 252Y/428L, 252Y/434S, and 428L/434S, and the numbering is according to the EU index. |
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Bibliography: | Application Number: US20080341769 |