DEGENERATE OLIGONUCLEOTIDES AND THEIR USES

The present invention provides a plurality of oligonucleotides comprising a semi-random sequence, wherein the semi-random sequence comprises degenerate nucleotides that are substantially non-complementary. Also provided are methods for using the plurality of oligonucleotides to amplify a population...

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Bibliographic Details
Main Authors HEUERMANN KENNETH E, WARD BRIAN
Format Patent
LanguageEnglish
Published 16.04.2009
Subjects
CHEMISTRY
COMBINATORIAL CHEMISTRY
DERIVATIVES THEREOF
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Summary:The present invention provides a plurality of oligonucleotides comprising a semi-random sequence, wherein the semi-random sequence comprises degenerate nucleotides that are substantially non-complementary. Also provided are methods for using the plurality of oligonucleotides to amplify a population of target nucleic acids.
Bibliography:Application Number: US20070872272