Compounds and Methods of Use Thereof

Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.

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Main Authors LI FRANCINE F, BURNS JAMES F, DIDSBURY JOHN R, VAN VLIET DAVID S, JONES MICHAEL L, SCHOENEN FRANK J, HAYDAR SIMON N, DYAKONOV TATYANA A, CABANA LEONARDO A, MIDDLEMISS DAVID, MATHEW JESSYMOL, MARKWORTH CHRISTOPHER J, COLLUPY GLENN C
Format Patent
LanguageEnglish
Published 01.01.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.
AbstractList Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.
Author MIDDLEMISS DAVID
LI FRANCINE F
CABANA LEONARDO A
DIDSBURY JOHN R
HAYDAR SIMON N
VAN VLIET DAVID S
MARKWORTH CHRISTOPHER J
JONES MICHAEL L
SCHOENEN FRANK J
COLLUPY GLENN C
DYAKONOV TATYANA A
BURNS JAMES F
MATHEW JESSYMOL
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– fullname: VAN VLIET DAVID S
– fullname: JONES MICHAEL L
– fullname: SCHOENEN FRANK J
– fullname: HAYDAR SIMON N
– fullname: DYAKONOV TATYANA A
– fullname: CABANA LEONARDO A
– fullname: MIDDLEMISS DAVID
– fullname: MATHEW JESSYMOL
– fullname: MARKWORTH CHRISTOPHER J
– fullname: COLLUPY GLENN C
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Snippet Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Compounds and Methods of Use Thereof
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