Compounds and Methods of Use Thereof

Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.

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Bibliographic Details
Main Authors	LI FRANCINE F, BURNS JAMES F, DIDSBURY JOHN R, VAN VLIET DAVID S, JONES MICHAEL L, SCHOENEN FRANK J, HAYDAR SIMON N, DYAKONOV TATYANA A, CABANA LEONARDO A, MIDDLEMISS DAVID, MATHEW JESSYMOL, MARKWORTH CHRISTOPHER J, COLLUPY GLENN C
Format	Patent
Language	English
Published	01.01.2009
Subjects	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:	Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.
Bibliography:	Application Number: US20050718277