Bicyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors

The present invention provides a compound of formula I wherein one of A and B is hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X is O, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need ther...

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Main Authors AGARWAL ATUL, YAMAMURA ITSUKI, ABE TAKAO, MANSOUR TAREK SUHAYL, LIN YANG-I, SUM FUK-WAH, VENKATESAN ARANAPAKAM MUDUMBAI, SANTOS OSVALDO DOS, TAKASAKI TSUYOSHI
Format Patent
LanguageEnglish
Published 18.12.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a compound of formula I wherein one of A and B is hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X is O, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.
Bibliography:Application Number: US20080195706