Formulation, Solubilization, Purification, and Refolding of Tissue Factor Pathway Inhibitor

Compositions are described that are suitable for formulating TFPI. Solubilizers and stabilizers facilitate the preparation of pharmaceutically acceptable compositions of TFPI at various concentrations.

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Bibliographic Details
Main Authors PATTISON GREGORY L, ARVE BO H, DORIN GLENN J, MADANI HASSAN, TSANG MICHAEL, JOHNSON KIRK, JOHNSON GARY V, CHEN BAO-LU, BILD GARY S, HALENBECK ROBERT F, HORA MANINDER S, RANA RAISHARAN K, GUSTAFSON MARK E
Format Patent
LanguageEnglish
Published 13.11.2008
Subjects
CHEMISTRY
FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Summary:Compositions are described that are suitable for formulating TFPI. Solubilizers and stabilizers facilitate the preparation of pharmaceutically acceptable compositions of TFPI at various concentrations.
Bibliography:Application Number: US20070697188