CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS

The present invention relates to compounds that bind to chemokine receptors, and having the formula wherein each A, X, Y, R1, R2 and R3 are substituents. The present invention also relates to methods of using such compounds, such as in treating HIV infection and inflammatory conditions such as rheum...

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Main Authors BRIDGER GARY J, SCHOLS DOMINIQUE, SKERLJ RENATO, BAIRD IAN, CHEN GANG, MCEACHERN ERNEST J, KALLER AL, SKUPINSKA KRYSTYNA, HARWIG CURTIS, ZHU YONGBAO
Format Patent
LanguageEnglish
Published 16.10.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to compounds that bind to chemokine receptors, and having the formula wherein each A, X, Y, R1, R2 and R3 are substituents. The present invention also relates to methods of using such compounds, such as in treating HIV infection and inflammatory conditions such as rheumatoid arthritis. Furthermore, the present invention relates to methods to elevate progenitor and stem cell counts, as well as methods to elevate white blood cell counts, using such compounds.
Bibliography:Application Number: US20070936047