DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS

A compound of the formula (I) wherein the variables X1 to X10, R1 to R7 including R3', E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity an...

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Main Authors DE LA TORRE MARTA GARCIA, HOLLOWAY WILLIAM GLEN, CHAPPELL MARK DONALD, STUCKY RUSSELL DEAN, WOLFE CHAD NOLAN, QUIMBY STEVEN JAMES, TAKEUCHI KUMIKO, SIEGEL MILES GOODMAN, MITCH CHARIES HOWARD, FRITZ JAMES ERWIN, MATT JAMES EDWARD, DIAZ BUEZO NURIA, SMITH DANA RAE, BLANCO-PILLADO MARIA-JESUS, PEDREGAL-TERCERO CONCEPCION, THOMAS ELIZABETH MARIE
Format Patent
LanguageEnglish
Published 16.10.2008
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A compound of the formula (I) wherein the variables X1 to X10, R1 to R7 including R3', E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.
Bibliography:Application Number: US20080052994