Tetrahydro-pyrimidoazepines as modulators of TRPV1

Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by TRPV1. Thus, the compounds may be-administered to treat,...

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Main Authors MCCLURE KELLY J, MERIT JEFFREY E, ALLISON BRETT D, BREITENBUCHER JAMES G, HAWRYLUK NATALIE A, LEBSACK ALEC D, HACK MICHAEL D, BRANSTETTER BRYAN J
Format Patent
LanguageEnglish
Published 27.09.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by TRPV1. Thus, the compounds may be-administered to treat, e.g., pain, itch, cough, asthma, or inflammatory bowel disease.
AbstractList Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by TRPV1. Thus, the compounds may be-administered to treat, e.g., pain, itch, cough, asthma, or inflammatory bowel disease.
Author BRANSTETTER BRYAN J
MERIT JEFFREY E
ALLISON BRETT D
MCCLURE KELLY J
HAWRYLUK NATALIE A
BREITENBUCHER JAMES G
HACK MICHAEL D
LEBSACK ALEC D
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– fullname: HAWRYLUK NATALIE A
– fullname: LEBSACK ALEC D
– fullname: HACK MICHAEL D
– fullname: BRANSTETTER BRYAN J
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Snippet Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Tetrahydro-pyrimidoazepines as modulators of TRPV1
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