Tetrahydro-pyrimidoazepines as modulators of TRPV1

Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by TRPV1. Thus, the compounds may be-administered to treat,...

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Bibliographic Details
Main Authors MCCLURE KELLY J, MERIT JEFFREY E, ALLISON BRETT D, BREITENBUCHER JAMES G, HAWRYLUK NATALIE A, LEBSACK ALEC D, HACK MICHAEL D, BRANSTETTER BRYAN J
Format Patent
LanguageEnglish
Published 27.09.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by TRPV1. Thus, the compounds may be-administered to treat, e.g., pain, itch, cough, asthma, or inflammatory bowel disease.
Bibliography:Application Number: US20070726756