Novel compounds that are ERK inhibitors

Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also di...

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Main Authors DESAI JAGDISH, SAMATAR AHMED A, WU YIJI, SHIPPS GERALD W.JR, KELLY JOSEPH M, DENG YONGQI, NAN YANG, WANG TONG, PALIWAL SUNIL, SIDDIQUI M. A, DOLL RONALD, SHIH NENG-YANG, WANG JAMES J, HRUZA ALAN W, MADISON VINCENT, DONG YOUHAO, BOGA SOBHANA B, XIAO LI, ZHU HUGH, COOPER ALAN, TSUI HONUNG, SUN ROBERT, CELEBI AZIM A
Format Patent
LanguageEnglish
Published 16.08.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
Bibliography:Application Number: US20060636954