Targeted nanoparticles for magnetic resonance imaging

In some embodiments, the present invention is directed to novel targeted contrast agents for magnetic resonance imaging (MRI). The present invention is also directed to methods of making such targeted MRI contrast agents, and to methods of using such MRI contrast agents. Typically, such targeted MRI...

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Main Authors MOASSER BAHRAM, WOOD NICHOLE L, BAILLIE MARK T, BONITATEBUS PETER J.JR, BELETSKII ANTON, BALES BRIAN C, TORRES ANDREW S, SYUD FAISAL A, KULKARNI AMIT M
Format Patent
LanguageEnglish
Published 21.06.2007
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Summary:In some embodiments, the present invention is directed to novel targeted contrast agents for magnetic resonance imaging (MRI). The present invention is also directed to methods of making such targeted MRI contrast agents, and to methods of using such MRI contrast agents. Typically, such targeted MRI contrast agents provide enhanced relaxivity, improved signal-to-noise, targeting ability, and resistance to agglomeration. Methods of making such MRI contrast agents typically afford better control over particle size, and methods of using such MRI contrast agents typically afford enhanced blood clearance rates and biodistribution.
Bibliography:Application Number: US20050304028