CANINE TUMOR TREATMENT METHOD, PHARMACEUTICAL FORMULATION APPLIED THERETO, AND METHOD OF CRYOGENICALLY PRESERVING CELLS USED THEREWITH

A treatment for tumorous canines and a method of preparing, cultivating, and cryogenically preserving the pharmaceutical formulation used in the treatment. Canine lymphocytes are activated and expanded in the presence of a combination of anti-canine CD3 antibodies and interleukin-2 (IL-2) (preferabl...

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Bibliographic Details
Main Authors OSUMI KAZUOKI, IINUMA AKIKO, BAMBA KENZO, KUROIWA YASUYUKI, SEKINE TERUAKI, ISHII HIROSHI
Format Patent
LanguageEnglish
Published 08.03.2007
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:A treatment for tumorous canines and a method of preparing, cultivating, and cryogenically preserving the pharmaceutical formulation used in the treatment. Canine lymphocytes are activated and expanded in the presence of a combination of anti-canine CD3 antibodies and interleukin-2 (IL-2) (preferably anti-canine CD3 antibodies and human interleukin-2 (human IL-2)) and administered to tumorous dogs. Following treatment, the canine tumors were observed to be in regression while no serious side effects were noted. Quality-of-life improvements were observed in the form of the animals' ability to walk increased distances and improved coat appearance.
Bibliography:Application Number: US20060465892