Post-transcriptional regulation of gene expression

The invention provides transgenic plants having within their genome DNA that includes an exogenous gene encoding a polypeptide and having in its 3' untranslated region a destabilizing sequence, whereby the polypeptide is expressed at a lower level in seed of the transgenic plants relative to ex...

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Bibliographic Details
Main Authors ULMASOV TIM N, THAI KWAN Y, DABROWSKI JOHN P, WANG QI, HOUSE IDA M
Format Patent
LanguageEnglish
Published 11.01.2007
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NEW PLANTS OR PROCESSES FOR OBTAINING THEM
PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TRAPPING
VINEGAR
WINE
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Summary:The invention provides transgenic plants having within their genome DNA that includes an exogenous gene encoding a polypeptide and having in its 3' untranslated region a destabilizing sequence, whereby the polypeptide is expressed at a lower level in seed of the transgenic plants relative to expression in the absence of the destabilizing sequence. Also disclosed are methods for post-transcriptionally decreasing the message stability of a gene of interest in a plant that involve adding a destabilizing sequence to the 3' untranslated region of the gene of interest.
Bibliography:Application Number: US20060434556