Enhancement of nucleic acid amplification using double-stranded DNA binding proteins
Disclosed are methods and materials for enhancing the efficiency, specificity and/or specificity of nucleic acid amplification reactions (e.g., PCR amplification reactions). The disclosed inventions involve the use of nonspecific double-stranded DNA binding proteins in amplification reactions. The m...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
07.12.2006
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Subjects | |
Online Access | Get full text |
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Summary: | Disclosed are methods and materials for enhancing the efficiency, specificity and/or specificity of nucleic acid amplification reactions (e.g., PCR amplification reactions). The disclosed inventions involve the use of nonspecific double-stranded DNA binding proteins in amplification reactions. The methods described herein are useful in a wide variety of molecular biology applications including allele specific PCR. |
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Bibliography: | Application Number: US20060365383 |