Small molecule therapeutics and uses therefor

The invention provides polyamides which bind genes having expanded oligonucleotide repeat sequences, which binding modulates transcription. The invention further provides methods of modulation of the transcription of such genes, and the use of polyamides as therapeutic agents to treat diseases assoc...

Full description

Saved in:
Bibliographic Details
Main Authors BURNETT RYAN, DERVAN PETER B, MELANDER CHRISTIAN, GOTTESFELD JOEL M
Format Patent
LanguageEnglish
Published 30.11.2006
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The invention provides polyamides which bind genes having expanded oligonucleotide repeat sequences, which binding modulates transcription. The invention further provides methods of modulation of the transcription of such genes, and the use of polyamides as therapeutic agents to treat diseases associated with such genes.
Bibliography:Application Number: US20060416381