Assay for detection of translocase enzyme activity in drug screening

The invention provides a method for assaying the activity of the translocase enzyme involved in peptidoglycan biosynthesis in bacteria using scintillation proximity assay methodology. The method is suitable for high throughput screening of potential anti-bacterial drugs.

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Bibliographic Details
Main Authors SOLAPURE SURESH, DESOUSA SUNITA M
Format Patent
LanguageEnglish
Published 03.08.2006
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The invention provides a method for assaying the activity of the translocase enzyme involved in peptidoglycan biosynthesis in bacteria using scintillation proximity assay methodology. The method is suitable for high throughput screening of potential anti-bacterial drugs.
Bibliography:Application Number: US20060326486