Exogenous protein expression system in an avian system

• Main Authors: SAMARUT JACQUES, PAIN BERTRAND, KUNITA RYOTA, CHAMPION-ARNAUD PATRICK, VALARCHE ISABELLE, SOBCZYK ANDRE
• Format: Patent
• Language: English
• Published: 13.10.2005
• Edition: 7
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; CARE OF BIRDS, FISHES, INSECTS; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FISHING; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; FORESTRY; HUMAN NECESSITIES; HUNTING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NEW BREEDS OF ANIMALS; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; TRAPPING; VINEGAR; WINE

The invention concerns the use of an avian cell for producing an exogenous protein of interest in an animal belonging to the avian species, said cell being transformed by an expression vector comprising the gene coding for said protein, said cell being introduced in the sub-germinal cavity of an embryo, the blood stream of the embryo or being used as nucleus source for nuclear transfer into an avian egg enucleated or not, or whereof the chromosomes have been destroyed.