Method of treating abnormal cell growth using indolinone compounds

The invention provides a method of treating abnormal cell growth in a mammal, such as a human, by administering to the mammal a therapeutically effective amount of a composition including one or both of 5-(5-fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid...

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Bibliographic Details
Main Authors BELLO CARLO L, PATYNA SHEM J, MASSIMINI GIORGIO P, SCIGALLA PAUL, KELSEY STEPHEN
Format Patent
LanguageEnglish
Published 18.08.2005
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides a method of treating abnormal cell growth in a mammal, such as a human, by administering to the mammal a therapeutically effective amount of a composition including one or both of 5-(5-fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)-amide and 5-(5-fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-ethylaminoethyl)-amide, or pharmaceutically acceptable salts, solvates or hydrates thereof, for at least one cycle of an intermittent dosing regimen.
Bibliography:Application Number: US20040991244