Delivery system for growth hormone releasing peptides

A system for delivering a growth hormone releasing peptide including a peptide, or a pharmaceutically acceptable salt form thereof, alternatively conjugated to a polymer via a biodegradable bond and dissolved in a liquid medium. Because extra-cellular fluids in vivo provide the appropriate environme...

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Bibliographic Details
Main Author OWOC JOHN H
Format Patent
LanguageEnglish
Published 28.07.2005
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A system for delivering a growth hormone releasing peptide including a peptide, or a pharmaceutically acceptable salt form thereof, alternatively conjugated to a polymer via a biodegradable bond and dissolved in a liquid medium. Because extra-cellular fluids in vivo provide the appropriate environment to efficiently degrade peptides, the growth hormone releasing peptide will maintain chemical integrity and remain substantially coupled to the polymer while circulating through the body. The therapeutic agent is, therefore, protected from degradation and clearance.
Bibliography:Application Number: US20050041575