Deazapurines and uses thereof

The present invention provides compounds having formula (I), wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and pro...

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Main Authors KIKUCHI KOUICHI, DAUN JANE, DAVIS HEATHER A, JIANG YIMIN, TREMBLAY LYNDA, KOBAYASHI SEIICHI, PESANT MARC, LI XIANG-YI, SPYVEE MARK, GUSOVSKY FABIAN, ZHAO YAN (JANET), KANEKO TOSHIHIKO, SELETSKY BORIS M, MURAMOTO KENZO, OHI NORIHITO, DEACOSTA BRUCE, LESCARBEAU ANDRE, YOKOHAMA HIROMITSU, ZHENG WANJUN, HISHINUMA IEHARU, YAO YE
Format Patent
LanguageEnglish
Published 09.06.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds having formula (I), wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.
Bibliography:Application Number: US20050500840