Polymorphs of clopidogrel hydrochloride and their use as antithrombic compounds

The invention relates to crystalline forms I and II methyl-(S)-(+)-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2.c]pyridine-5-yl)-acetate hydrochloride of the Formula (I) and hydrates thereof, a process for the preparation thereof and pharmaceutical compositions containing the same. The new polymorp...

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Main Authors FARKAS BELA, DONATH GYORGYI V, KORTVELYESSY GYULANE, NAGY KALMAN, BARKOCZY JOZSEF, SZENT KIRALLYI ZSUZSA, NAGY PETER K, GREGOR TAMAS, SIMIG GYULA
Format Patent
LanguageEnglish
Published 26.05.2005
Edition7
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Summary:The invention relates to crystalline forms I and II methyl-(S)-(+)-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2.c]pyridine-5-yl)-acetate hydrochloride of the Formula (I) and hydrates thereof, a process for the preparation thereof and pharmaceutical compositions containing the same. The new polymorphs according to the invention exhibit blood platelet aggregation inhibiting and antithrombotic effect.
Bibliography:Application Number: US20040504042