Mammalian cell lines specifically deficient in O-linked glycosylation
Genetically modified cell lines that express a UDP-galactose 4-epimerase (GALE) capable of interconverting UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc), but essentially incapable of interconverting UDP-N-acetylgalactosamine (UDP-galNAc) and UDP-N-acetylglucosamine (UDP-glcNAc).
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Main Authors | , , , , |
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Format | Patent |
Language | English |
Published |
26.05.2005
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | Genetically modified cell lines that express a UDP-galactose 4-epimerase (GALE) capable of interconverting UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc), but essentially incapable of interconverting UDP-N-acetylgalactosamine (UDP-galNAc) and UDP-N-acetylglucosamine (UDP-glcNAc). |
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Bibliography: | Application Number: US20040781012 |