Identification and isolation of novel polypeptides having PDZ domains and methods of using same

The invention described herein encompasses the identification and isolation of polypeptides having PDZ domains or functional equivalents thereof. Various methods of use of these polypeptides are described including, but not limited to, targeted drug discovery. The invention also includes nucleotide...

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Bibliographic Details
Main Authors PIROZZI GREGORIO, HERRERO JUAN, UVEGES ALBERT
Format Patent
LanguageEnglish
Published 26.05.2005
Edition7
Subjects
CHEMISTRY
ELECTRIC COMMUNICATION TECHNIQUE
ELECTRICITY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SELECTING
TESTING
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Summary:The invention described herein encompasses the identification and isolation of polypeptides having PDZ domains or functional equivalents thereof. Various methods of use of these polypeptides are described including, but not limited to, targeted drug discovery. The invention also includes nucleotide sequences encoding novel PDZ domains and the proteins encoded thereby. The invention additionally provides for various peptide recognition units that bind to PDZ domains. The present invention also encompasses nucleotide sequences encoding novel WW domains and the polypeptides encoded thereby.
Bibliography:Application Number: US20040785819