Method of decreasing sebum production

Cosmetic compositions and methods of decreasing sebum production by contacting sebocytes with a fatty acid synthase inhibitor, including cerulenin, triclosan, alpha-methylene-gamma-butyrolactone, and EGCG, as well as mixtures thereof and analogs thereof. The invention further relates to a cosmetic m...

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Bibliographic Details
Main Authors CAMPBELL KIMBERLY MARIE, BAJOR JOHN STEVEN, KNAGGS HELEN ELIZABETH, D'ARCANGELIS ALEXANDRA DRAGANESCU
Format Patent
LanguageEnglish
Published 10.03.2005
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Summary:Cosmetic compositions and methods of decreasing sebum production by contacting sebocytes with a fatty acid synthase inhibitor, including cerulenin, triclosan, alpha-methylene-gamma-butyrolactone, and EGCG, as well as mixtures thereof and analogs thereof. The invention further relates to a cosmetic method of identifying sebum production inhibiting actives comprising contacting the active with FAS and detecting a reduction in sebum amount production in sebocytes.
Bibliography:Application Number: US20030658876