Modified Wee1, crystals of peptide: inhibitor complexes containing such modified Wee1, and methods of use thereof
Modified Wee1 peptides, polynucleotides encoding those peptides, and methods for purifying the peptides and crystallizing them as peptide: inhibitor complexes have been discovered. The three-dimensional structure of Wee1, including the ATP substrate binding site, and uses of this information in the...
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Main Authors | , , , , , , |
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Format | Patent |
Language | English |
Published |
17.02.2005
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | Modified Wee1 peptides, polynucleotides encoding those peptides, and methods for purifying the peptides and crystallizing them as peptide: inhibitor complexes have been discovered. The three-dimensional structure of Wee1, including the ATP substrate binding site, and uses of this information in the design and screening of compounds that may associate with Wee1, or peptides structurally related thereto, have also been discovered. |
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Bibliography: | Application Number: US20040837652 |