Compositions comprising plant-derived polyphenolic compounds and inhibitors of reactive oxygen species and methods of using thereof

Disclosed are methods for treating, preventing, or inhibiting diseases and disorders associated with NF-kappaB activation including proliferative diseases such as cancer and inflammatory diseases such as pancreatitis in a subject which comprises administering at least one polyphenolic compound and/o...

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Bibliographic Details
Main Authors BOROS LASZLO G, EIBL GUIDO, PANDOL STEPHEN J, YAZBECK MOUSSA, GUKOVSKAYA ANNA
Format Patent
LanguageEnglish
Published 23.12.2004
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed are methods for treating, preventing, or inhibiting diseases and disorders associated with NF-kappaB activation including proliferative diseases such as cancer and inflammatory diseases such as pancreatitis in a subject which comprises administering at least one polyphenolic compound and/or at least one inhibitor of reactive oxygen species to the subject. Also disclosed are pharmaceutical compositions comprising at least one polyphenolic compound and/or at least one inhibitor of reactive oxygen species. The polyphenolic compound may be derived or isolated from plants. In some embodiments, the polyphenolic compound is a flavonoid. In other embodiments, the polyphenolic compound is a non-flavonoid. Other methods and kits are also disclosed as well as pharmaceutical compositions.
Bibliography:Application Number: US20040824597