Process for the preparation of 3-spiro'cyclohexam-1,3'-'3h!indolin-2'-one! derivatives

The invention relates to a process for the preparation of a compound of the formula (I) by reacting a compound of the formula (II) with a compound of the formula (III) characterised by dissolving the compounds of the formula (II) and formula (III) in a water-inmiscible organic solvent in the presenc...

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Main Authors GONCZI CSABA, SANTANE ANDREA CSUTOR, SZOMOR TOBORNE, HERMECZ ISTVAN, HAJDU FELIX, HEJA GERGELY, HEJA GERGELYNE, NAGY LAJOS, SZVOBODA GYORGYNE, MAJLATH CSILLA, CSIKOS EVA
Format Patent
LanguageEnglish
Published 11.11.2004
Edition7
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Summary:The invention relates to a process for the preparation of a compound of the formula (I) by reacting a compound of the formula (II) with a compound of the formula (III) characterised by dissolving the compounds of the formula (II) and formula (III) in a water-inmiscible organic solvent in the presence of a phase transfer catalyst, reacting with a.) an aqeuos solution of a base, or b.) a base in solid form directly and if desired transforming the compound of formula (I) thus obtained into its salt.
Bibliography:Application Number: US20040485133