Integrin antagonists

Novel biphenyl derivatives of the general formula (I), in which A, X, R , R<1'>, R<1''>, R R<2'>, R<2''> and n are as defined in Patent claim 1, stereoisomers thereof and physiologically acceptable salts or solvates thereof are novel inhibitors o...

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Bibliographic Details
Main Authors JONCZYK ALFRED, GOODMAN SIMON, STAEHLE WOLFGANG, SCHADT OLIVER
Format Patent
LanguageEnglish
Published 12.08.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel biphenyl derivatives of the general formula (I), in which A, X, R , R<1'>, R<1''>, R R<2'>, R<2''> and n are as defined in Patent claim 1, stereoisomers thereof and physiologically acceptable salts or solvates thereof are novel inhibitors of integrin receptors, in particular of the alphavbeta3, alphavbeta5 and/or alphavbeta6 integrin receptors. The novel compounds can be used as medicaments.
Bibliography:Application Number: US20030479060