Ultra thin film transdermal/dermal or transmucosal/mucosal delivery system

• Main Authors: FAASSE ADRIAN L, CLEARY GARY W
• Format: Patent
• Language: English
• Published: 15.07.2004
• Edition: 7
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROSTHESES; TREATMENT OR PROTECTION OF EYES OR EARS

An ultra thin film transdermal, dermal, transmucosal, mucosal pharmaceutical delivery system is disclosed, which has a handle adhered by a first adhesive to an ultra thin film layer. The opposite side of the ultra thin film is coated with a second adhesive layer, and carries an active ingredient. The handle adheres firmly to the ultra thin film layer, but does not adhere to skin, mucosa, or the silicone coated surface of a release liner. A portion of the handle extends beyond an edge of the ultra thin film to facilitate separation of the film from the release liner, and handling thereof. The second adhesive is more aggressive with respect to the patient's skin than the first adhesive is with respect to the surface of the ultra thin film, whereby the handle can be peeled away from the ultra thin film after the film has been applied to the patient.