Generation of efficacy, toxicity and disease signatures and methods of use thereof

The invention provides methods of generating small molecule efficacy profiles and signature, small molecule toxicity profiles and signatures and small molecule disease profiles and signatures. The invention also provides methods of determining the efficacy and/or toxicity of unknown agents and drugs...

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Bibliographic Details
Main Authors MCCARROLL ROBERT MICHAEL, WIEGAND ROGER CHARLES, WEI DONG, LI LILY Y. T, ROSENBERG ALEXANDER FREDERIC, ROGERS JAMES ANTHONY, CROSAS MERCE
Format Patent
LanguageEnglish
Published 24.06.2004
Edition7
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The invention provides methods of generating small molecule efficacy profiles and signature, small molecule toxicity profiles and signatures and small molecule disease profiles and signatures. The invention also provides methods of determining the efficacy and/or toxicity of unknown agents and drugs in a subject and methods of diagnosing an unknown disease or disorder in a subject. The invention further provides methods of monitoring the progression or remission of a disease or disorder in a subject undergoing treatment and methods of measuring the effectiveness of treatment.
Bibliography:Application Number: US20020323493