Novel solid pharmaceutical dispersions

A novel solid pharmaceutical dispersion that improves the bioavailability of poorly water soluble drugs is produced by combining the drug with a polymer carrier such as polyvinylpyrrolidone. The drug is combined with the carrier without the need for using organic solvents or melting temperatures (fu...

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Bibliographic Details
Main Authors NESBITT RUSSELL U, PARIKH RITEN, REISCH ROBERT, GHEBRE-SELLASSIE ISAAC, FAWZI MAHDI B
Format Patent
LanguageEnglish
Published 10.06.2004
Edition7
Subjects
BABY COMFORTERS
CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES
DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY
DEVICES FOR RECEIVING SPITTLE
DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A novel solid pharmaceutical dispersion that improves the bioavailability of poorly water soluble drugs is produced by combining the drug with a polymer carrier such as polyvinylpyrrolidone. The drug is combined with the carrier without the need for using organic solvents or melting temperatures (fusion) through the use of a transition compound such as polyethylene glycol which partially solubilizes the drug and/or plasticizes the polymer.
Bibliography:Application Number: US20030726780