Oligomers and oligomeric segments of alpha-hydroxy carboxylic acids and alpha-amino acids

An enzymatic synthesis and composition of alpha-hydroxy carboxylic acid and alpha-amino acid or peptide co-oligomers is disclosed wherein a residue of the alpha-hydroxy carboxylic acid is linked to a residue of the alpha-amino acid or peptide by an amide linkage. Proteolytic enzyme papain catalyzes...

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Bibliographic Details
Main Authors SCHASTEEN CHARLES S, NAM PAUL K. S, LORBERT STEPHEN J, RAJESH MATHUR P, KAPILA SHUBHENDER, FORCINITI DANIEL
Format Patent
LanguageEnglish
Published 11.03.2004
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
SPIRITS
VINEGAR
WINE
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Summary:An enzymatic synthesis and composition of alpha-hydroxy carboxylic acid and alpha-amino acid or peptide co-oligomers is disclosed wherein a residue of the alpha-hydroxy carboxylic acid is linked to a residue of the alpha-amino acid or peptide by an amide linkage. Proteolytic enzyme papain catalyzes co-oligomerization of the alpha-hydroxy carboxylic acid and alpha-amino acid. The degree and distribution of oligomerization varies upon the type and concentrations of different reaction mixtures utilized and upon the length of allowed reaction time. The resultant oligomers may be provided to ruminants as bioavailable amino acid supplements that are resistant to degradation in the rumen.
Bibliography:Application Number: US20030609825