Therapeutic polypeptides, nucleic acids encoding same, and methods of use

• Main Authors: JI WEIZHEN, VERNET CORINE A.M, BURGESS CATHERINE E, WOLENC ADAM R, SHIMKETS RICHARD A, BOLDOG FERENC L, GUO XIAOJIA SASHA, LI LI, VOSS EDWARD Z, STONE DAVID J, EDINGER SHLOMIT R, KEKUDA RAMESH, ZHONG MEI, LEITE MARIO W, MAJUMDER KUMUD, RASTELLI LUCA, GORMAN LINDA, SPYTEK KIMBERLY A, LEPLEY DENISE M, HJALT TORD, ANDERSON DAVID W, MALYANKAR URIEL M, SMITHSON GLENNDA, RIEGER DANIEL K, CASMAN STACIE J, ELLERMAN KAREN, ZERHUSEN BRYAN D, MACDOUGALL JOHN R, MILLER CHARLES E, PADIGARU MURALIDHARA, GERLACH VALERIE, PATTURAJAN MEERA, PENA CAROL E. A, ALSOBROOK JOHN P, BAUMGARTNER JASON C
• Format: Patent
• Language: English
• Published: 04.03.2004
• Edition: 7
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.