REDIRECTION OF CELLULAR IMMUNITY BY RECEPTOR CHIMERAS

Disclosed is a method of directing a cellular response in a mammal by expressing in a cell of the mammal a chimeric receptor which causes the cells to specifically recognize and destroy an infective agent, a cell infected with an infective agent, a tumor or cancerous cell, or an autoimmune-generated...

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Bibliographic Details
Main Authors KOLANUS WALDEMAR, SEED BRIAN, ROMEO CHARLES
Format Patent
LanguageEnglish
Published 08.01.2004
Edition7
Subjects
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Summary:Disclosed is a method of directing a cellular response in a mammal by expressing in a cell of the mammal a chimeric receptor which causes the cells to specifically recognize and destroy an infective agent, a cell infected with an infective agent, a tumor or cancerous cell, or an autoimmune-generated cell. Also disclosed are cells which express the chimeric receptors and DNA encoding the chimeric receptors.
Bibliography:Application Number: US19990243008