Method for producing lamotrigine from alpha-oxo-2,3-dichlorophenyl acetamidino-aminoguanidino hydrazone by ring closure reaction

The present invention relates to a method for producing 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine (lamotrigine) by cyclization reaction from alpha-oxo-2,3-dichlorophenylacetamidino-aminoguanidino-hydrazone.

Saved in:
Bibliographic Details
Main Authors MATE ATTILA GERGELY, NYERGES MIKLOS, SCHNEIDER GEZA, GEGOE CSABA LEHEL, LUKACS FERENC, GARACZI SANDOR, ONDI LEVENTE
Format Patent
LanguageEnglish
Published 09.10.2003
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to a method for producing 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine (lamotrigine) by cyclization reaction from alpha-oxo-2,3-dichlorophenylacetamidino-aminoguanidino-hydrazone.
Bibliography:Application Number: US20030343225