Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use

• Main Authors: PEYMAN JOHN A, TCHERNEV VELIZAR T, BOLDOG FERENC L, LI LI, SHENOY SURESH G, STONE DAVID J, EDINGER SHLOMIT R, KEKUDA RAMESH, JU JINGFANG, RASTELLI LUCA, GANGOLLI ESHA A, SPYTEK KIMBERLY A, MEZES PETER D, VERNET CORINE A. M, SMITHSON GLENNDA, MALYANKAR URIEL M, CASMAN STACIE J, TAUPIER RAYMOND J, ZERHUSEN BRYAN D, HEYES MELVYN P, MACDOUGALL JOHN R, PADIGARU MURALIDHARA, MILLER CHARLES E, MAZUR ANN, GUO XIAOJIA, GERLACH VALERIE, CATTERTON ELINA, PATTURAJAN MEERA
• Format: Patent
• Language: English
• Published: 02.10.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.