Ligands specific for an isoform of the prion protein

Prion protein, PrP, ligands are provided, especially protease resistant and nuclease resistant ligands. Ligands selective for isoforms such as PrPSC can be prepared. In a related aspect, the PrP ligands are used in diagnostic tests for PrP. The ligands also have potential for a role in the developme...

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Bibliographic Details
Main Authors TAHIRI-ALAOUI ABDESSAMAD, HOPE JAMES, JAMES WILLIAM SIWARD
Format Patent
LanguageEnglish
Published 28.08.2003
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Prion protein, PrP, ligands are provided, especially protease resistant and nuclease resistant ligands. Ligands selective for isoforms such as PrPSC can be prepared. In a related aspect, the PrP ligands are used in diagnostic tests for PrP. The ligands also have potential for a role in the development of therapeutic methods for treatment of TSEs.
Bibliography:Application Number: US20020295798