Method and device for assaying molecules using RF integrated passive components

• Main Authors: SHMAGIN IRINA, BEUHLER ALLYSON, LACH LAWRENCE
• Format: Patent
• Language: English
• Published: 06.02.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; THEIR RELEVANT APPARATUS; TRANSPORTING; VINEGAR; WINE

A method and device of detecting a molecule, such as DNA or RNA, is provided. The device includes a substrate having an array of at least one biodetection site. The biodetection site is in contact with an electrical resonator. A biochemical probe is applied to the site and is subsequently interacted with the target biomolecule at the site. The magnetic properties of the biodetection site are measured and may be correlated with the presence and quantity of biomolecules at the site. Methods of using the device to detect the presence and determine the quantity of molecules at the site are also provided.