(7-(3-Carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine

The invention described herein relates to a process for the preparation of (7-(3-carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine (I), intermediates thereto and new forms and formulations thereof, including the zwitterion monohydrate of (I), suitable for pharmaceutical use.

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Bibliographic Details
Main Authors BRUCKNER ANNE, MACRAE JULIE ANN, FITZGERALD MICHAEL PAUL, NEWBURY TREVOR JACK, FISH PAUL VINCENT, STOREY RICHARD ANTHONY, BUTTERS MICHAEL
Format Patent
LanguageEnglish
Published 20.06.2002
Edition7
Subjects
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention described herein relates to a process for the preparation of (7-(3-carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine (I), intermediates thereto and new forms and formulations thereof, including the zwitterion monohydrate of (I), suitable for pharmaceutical use.
Bibliography:Application Number: US20010005587