Triterpene derivatives and remedies for liver diseases

A triterpene derivative useful for the treatment of hepatic disorders is disclosed. This compound comprises as an active ingredient a triterpene derivative represented by the following formula (I) or a salt thereof: wherein R1 represents a hydroxyl group, arylmethyloxy, lower alkoxy, or lower alkano...

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Bibliographic Details
Main Authors MINOWA NOBUTO, SASAKI KAZUE, NISHIYAMA SHOJI, KUZUHARA HIROYUKI
Format Patent
LanguageEnglish
Published 07.02.2002
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
STEROIDS
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Summary:A triterpene derivative useful for the treatment of hepatic disorders is disclosed. This compound comprises as an active ingredient a triterpene derivative represented by the following formula (I) or a salt thereof: wherein R1 represents a hydroxyl group, arylmethyloxy, lower alkoxy, or lower alkanoyloxy, R2 represents lower alkyl, lower alkenyl, -CH2OR5, formyl, -COOR6, or -CH2N(R7)R8, or R1 and R2 may combine with each other to form -O-C(R9)R10-O-CH2-, R3 and R4, which may be the same or different represent a hydrogen atom, a hydroxyl group, lower alkyl, lower alkenyl, aryl, hydroxymethyl, -N(R11)R12, formyl, -COOR6, or -OR13, or R3 and R4 may combine with each other to form oxo, hydroxyimino, or alkylidene and X represents O, CH2, or NH.
Bibliography:Application Number: US20010921983