Hydrazide and alkoxyamide angiogenesis inhibitors

Compounds having the formula are methionine aminopeptidase type 2 (MetAP2) inhibitors and are useful for inhibiting angiogenesis. Also disclosed are MetAP2-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.

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Bibliographic Details
Main Authors CRAIG RICHARD A, PATEL JYOTI R, BA-MAUNG NWE, YANG FAN, SHEPPARD GEORGE S, LYNCH LINDA M, KAWAI MEGUMI, WANG JIEYI
Format Patent
LanguageEnglish
Published 03.01.2002
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Compounds having the formula are methionine aminopeptidase type 2 (MetAP2) inhibitors and are useful for inhibiting angiogenesis. Also disclosed are MetAP2-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.
Bibliography:Application Number: US20010833917