Preparation for magnetic resonance diagnostics for oncological diseases, comprising deuterated 3-O-methylglucose, and diagnostic method using said preparation

The invention relates to medicine, particularly to agents for magnetic resonance diagnostics for oncological diseases. Developed for this purpose are a diagnostic preparation and a diagnostic method based on using said diagnostic preparation, in which a deuterated derivative of 3-O-methylglucose or...

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Main Authors Kiselevsky, Mikhail Valentinovich, Lesiv, Aleksei Valerievich, Gulyaev, Mikhail Vladimirovich, Polshakov, Vladimir Ivanovich, Dorofeeva, Evgeniya Olegovna, Kosenkov, Aleksei Viktorovich, Ivashkin, Pavel Evgenievich
Format Patent
LanguageEnglish
Published 15.10.2024
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Summary:The invention relates to medicine, particularly to agents for magnetic resonance diagnostics for oncological diseases. Developed for this purpose are a diagnostic preparation and a diagnostic method based on using said diagnostic preparation, in which a deuterated derivative of 3-O-methylglucose or a mixture of at least two different deuterated derivatives of 3-O-methylglucose is used as said preparation. The method according to the invention includes conducting magnetic resonance imaging and/or magnetic resonance spectroscopy on deuterium nuclei at a time after administration of the diagnostic preparation sufficient for the diagnostic preparation to accumulate in the tumor tissue of a subject in order to produce a magnetic resonance image and/or a magnetic resonance spectrum accordingly. The proposed method enables a highly informed diagnosis of oncological diseases.
Bibliography:Application Number: US201716765934