Preparation for magnetic resonance diagnostics for oncological diseases, comprising deuterated 3-O-methylglucose, and diagnostic method using said preparation

The invention relates to medicine, particularly to agents for magnetic resonance diagnostics for oncological diseases. Developed for this purpose are a diagnostic preparation and a diagnostic method based on using said diagnostic preparation, in which a deuterated derivative of 3-O-methylglucose or...

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Main Authors Kiselevsky, Mikhail Valentinovich, Lesiv, Aleksei Valerievich, Gulyaev, Mikhail Vladimirovich, Polshakov, Vladimir Ivanovich, Dorofeeva, Evgeniya Olegovna, Kosenkov, Aleksei Viktorovich, Ivashkin, Pavel Evgenievich
Format Patent
LanguageEnglish
Published 15.10.2024
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Summary:The invention relates to medicine, particularly to agents for magnetic resonance diagnostics for oncological diseases. Developed for this purpose are a diagnostic preparation and a diagnostic method based on using said diagnostic preparation, in which a deuterated derivative of 3-O-methylglucose or a mixture of at least two different deuterated derivatives of 3-O-methylglucose is used as said preparation. The method according to the invention includes conducting magnetic resonance imaging and/or magnetic resonance spectroscopy on deuterium nuclei at a time after administration of the diagnostic preparation sufficient for the diagnostic preparation to accumulate in the tumor tissue of a subject in order to produce a magnetic resonance image and/or a magnetic resonance spectrum accordingly. The proposed method enables a highly informed diagnosis of oncological diseases.
Bibliography:Application Number: US201716765934