Isoindolinone inhibitors of the MDM2-P53 interaction having anticancer activity
The invention provides a compound of formula (I):or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims.Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compo...
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Format | Patent |
Language | English |
Published |
27.08.2024
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Abstract | The invention provides a compound of formula (I):or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims.Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds. |
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AbstractList | The invention provides a compound of formula (I):or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims.Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds. |
Author | Peach, Joanne Mitchell, Dale Robert Cano, Celine Florence Holvey, Rhian Sara Buck, Ildiko Maria Rees, David Charles Griffin, Roger John Osborne, James Daniel Johnson, Christopher Norbert St. Denis, Jeffrey David Cons, Benjamin David Hardcastle, Ian Robert Hirst, Kim Louise Watson, David Wyn Golding, Bernard Thomas Noble, Martin Edward Mäntylä Tamanini, Emiliano Chessari, Gianni Whittaker, Benjamin Paul Howard, Steven Lewis, Arwel Miller, Duncan Charles |
Author_xml | – fullname: Peach, Joanne – fullname: Noble, Martin Edward Mäntylä – fullname: Mitchell, Dale Robert – fullname: Cano, Celine Florence – fullname: Miller, Duncan Charles – fullname: Osborne, James Daniel – fullname: Whittaker, Benjamin Paul – fullname: Chessari, Gianni – fullname: Cons, Benjamin David – fullname: Holvey, Rhian Sara – fullname: Tamanini, Emiliano – fullname: Lewis, Arwel – fullname: Buck, Ildiko Maria – fullname: Griffin, Roger John – fullname: Watson, David Wyn – fullname: Hirst, Kim Louise – fullname: Rees, David Charles – fullname: St. Denis, Jeffrey David – fullname: Golding, Bernard Thomas – fullname: Hardcastle, Ian Robert – fullname: Johnson, Christopher Norbert – fullname: Howard, Steven |
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Snippet | The invention provides a compound of formula (I):or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are... |
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SubjectTerms | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | Isoindolinone inhibitors of the MDM2-P53 interaction having anticancer activity |
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