Drug-conjugates with a targeting molecule and two different drugs
There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein. More specifically, the present disclosure attaches a first drug conjugate to a dual Cysteine residue on a targeting protein and a second...
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Main Authors | , , , , , , |
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Format | Patent |
Language | English |
Published |
21.05.2024
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Subjects | |
Online Access | Get full text |
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Summary: | There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein. More specifically, the present disclosure attaches a first drug conjugate to a dual Cysteine residue on a targeting protein and a second drug conjugate with a different drug to a Lys residue on the targeting protein. |
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Bibliography: | Application Number: US202017037370 |