Method for reducing or inactivating viral and microbial content in the processes for the manufacture of pancreatin

A pancreatin preparation having reduced viral infectivity includes one or more pancreatin enzymes and peracetic acid (PAA). At least one pancreatin enzyme may be derived from an animal source such as a porcine pancreas gland. In a particular embodiment, the one or more pancreatin enzymes are selecte...

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Main Authors Anhalt, Karla, Romich, Mark, Wang, Yan, Manning, Kenneth S, Nielsen, Dustin, Akula, Anisha, Fritz, Carmen, Crowley, Colin, Restivo, Jon, Ruf, Ryan, Spangenberg, Dana
Format Patent
LanguageEnglish
Published 09.04.2024
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Summary:A pancreatin preparation having reduced viral infectivity includes one or more pancreatin enzymes and peracetic acid (PAA). At least one pancreatin enzyme may be derived from an animal source such as a porcine pancreas gland. In a particular embodiment, the one or more pancreatin enzymes are selected from the group consisting of lipases, proteases, and amylases.
Bibliography:Application Number: US201816108930