Substituted bicyclic heterocyclic compounds as PRMT5 inhibitors

The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of t...

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Main Authors Hajare, Anil Kashiram, Palle, Venkata P, Gore, Balasaheb Arjun, Sindkhedkar, Milind Dattatraya, Nair, Prathap Sreedharan, Sethi, Sachin, Kamboj, Rajender Kumar, Lagad, Dipak Raychand, Gudade, Ganesh Bhausaheb, Kulkarni, Chaitanya Prabhakar, Pawar, Chetan Sanjay, Tryambake, Mahadeo Bhaskar, Kulkarni, Sanjeev Anant
Format Patent
LanguageEnglish
Published 09.04.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.
Bibliography:Application Number: US202217738370