Stable, concentrated radionuclide complex solutions

The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradat...

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Bibliographic Details
Main Authors de Palo, Francesco, Brambati, Clementina, Tesoriere, Giovanni, Fugazza, Lorenza, Chicco, Daniela, Barbato, Donato, Mariani, Maurizio
Format Patent
LanguageEnglish
Published 20.02.2024
Subjects
CHEMISTRY
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
FERROUS OR NON-FERROUS ALLOYS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRETREATMENT OF RAW MATERIALS
PRODUCTION AND REFINING OF METALS
TREATMENT OF ALLOYS OR NON-FERROUS METALS
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Summary:The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage.
Bibliography:Application Number: US202016827606