Sequencing methods and compositions for prenatal diagnoses
The invention provides methods for determining aneuploidy and/or fetal fraction in maternal samples comprising fetal and maternal cfDNA by massively parallel sequencing. The method comprises a novel protocol for preparing sequencing libraries that unexpectedly improves the quality of library DNA whi...
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Main Authors | , , , , |
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Format | Patent |
Language | English |
Published |
30.01.2024
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Subjects | |
Online Access | Get full text |
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Summary: | The invention provides methods for determining aneuploidy and/or fetal fraction in maternal samples comprising fetal and maternal cfDNA by massively parallel sequencing. The method comprises a novel protocol for preparing sequencing libraries that unexpectedly improves the quality of library DNA while expediting the process of analysis of samples for prenatal diagnoses. |
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Bibliography: | Application Number: US202117193279 |