Methods for quantitative and enhanced-contrast molecular medical imaging using cross-modality correction for differing tracer kinetics

An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to...

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Bibliographic Details
Main Authors Pogue, Brian William, Davis, Scott C, Tichauer, Kenneth M
Format Patent
LanguageEnglish
Published 14.11.2023
Subjects
CALCULATING
COMPUTING
COUNTING
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
MEDICAL OR VETERINARY SCIENCE
PHYSICS
SURGERY
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Summary:An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.
Bibliography:Application Number: US201715402077